A Review on “Skin Boosters”: Hyaluronic Acid, Poly-L-lac...

The term “skin booster” was introduced in 2015 to describe the use of “Restylane Vital” and “Vital Light” hyaluronic acid filler products to improve skin aging and reduce wrinkles by supplying hyaluronic acid filler to the dermis. Previously, hyaluronic acid fillers were mainly used to increase skin volume. Skin boosters are a range of ingredients used to improve dermal conditions. Although Restylane Skinboosters such as “Restylane Vital” and “Vital Light” are registered trademarks, the term “skin booster” is now commonly used by the public, just as “Botox” is used for botulinum toxin produced by Allergan. The article discusses representative skin booster ingredients, but there is no clear definition of the term. The authors believe that skin boosters include various ingredients used to improve the extracellular matrix of the dermis to enhance the skin’s condition. It is important to note that products approved as cosmetics in Korea but delivered through injection to the dermal layer or below violate medical law. Therefore, caution should be exercised when selecting products. This article focuses on introducing five main ingredients that have recently become issues: hyaluronic acid, polydeoxyribonucleotide, polynucleotide, oligonucleotide, and amino acids. The article discusses provided unbiased descriptions of their clinical experiences to help readers make informed choices. In the article it is not promoted with specific products for profit, and the product evaluation is based purely on clinical experience. In conclusion, skin boosters are a range of ingredients that improve the dermal condition of the skin, and this article provides information on popular ingredients to help readers choose the right products.

Automated Syringe Assist Device for Massive Lipolytic Agent ...

Background and Objectives
This study aims to improve the inconvenience of injecting a conventional syringe. We propose a pen-type injection-assisting device that can automatically apply pressure to a replaceable cylinder using an electric motor. Generally, injection with a syringe is one of the most important techniques in clinical practice and is particularly used when lipolysis or anesthetic agents are injected. Currently, a general syringe is used for lipolysis injection, and a large amount of drugs are injected, resulting in significant fatigue of the fingers of medical personnel. In addition, it is difficult to inject with a syringe while maintaining a constant pressure due to fatigue.
Materials and Methods
The assisting device is demonstrated as a model for a 3D automatic syringe assist device. The main body is a plastic syringe detacher, and all internal accessories were made of plastic, except for the holder and motor which are in the form of a metal clip.
The present invention is a device that uses an electric motor and a cogwheel connected thereto to apply positive pressure to a cylinder while holding the syringe with one hand, like a pen, and pressing a presser bar with the push of a button.
By improving discomfort during the injection process due to manipulation of both hands, side effects, such as pain and hematoma that patients may experience after surgery can be alleviated.

Supplementary video file: This article contains supplementary material (It is available at

The Effect of Polydioxanone Thread and Platelet Rich Plasma ...

Background and Objectives
Myofascial pelvic pain is a major component of chronic pelvic pain. Effective treatments are available to reduce pain, including myofascial tender point release. The study investigated the safety, feasibility and early outcomes of releasing myofascial tender point by polydioxanone thread and platelet rich plasma treatment in myofascial pelvic pain patients.
Materials and Methods
Twenty myofascial pelvic pain patients underwent polydioxanone thread and platelet rich plasma treatment. After autologous platelet rich plasma was injected into the pelvic muscles through vaginal access, a multi-braided polydioxanone thread was inserted into the middle and deep layers of the pelvic muscles. Pre- and post-procedural satisfaction surveys and Female Sexual Function Index scores (FSFI) were obtained. Vaginal manometry measured mobility and pressure of pelvic floor muscles. The patients were followed-up at 3 and 6 months after the procedure.
At 3-months after the procedure, 65% of the patients answered positively on the improvement of symptoms and tenderness, 35% answered no difference, and none answered worsening. At this period, FSFI did not show a significant change in any of the six categories. After six months, however, there was a statistically significant improvement in all the indices except for sexual desire (p < 0.05).
Pelvic floor muscle targeted polydioxanone thread insertion and platelet rich plasma injection is safe and feasible, and may minimize pelvic pain without side effects such as infection or bleeding. It may potentially improve urinary control and sexual function by releasing myofascial tenderness.
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Article Type | Date
메디톡스 배너 이미지 엘라비에 배너 이미지 파마리서치 배너 이미지 이루다 배너 이미지
ShenB 배너 이미지 원텍 올리지오 배너 이미지 Novo Nordisk 배너 이미지 시지바이오 배너 이미지 쉬앤비 배너 이미지 멀츠 배너 이미지


  • Automated syringe assist device for massive lipolytic agent injection

  • 【V-OLET】 Clinical Guideline: Deoxycholic Acid Injection for Submental Fat Reduction