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Original Article

The AESTHETICS 2020; 1(2): 57-62

Published online October 31, 2020

© Korean Association For Laser Dermatology And Trichology

Stability Is Important to Clinicians When Selecting a Botulinum Toxin Product

Seung Min Oh, MD, MMBA1, Bong Cheol Kim, MD2, Min Ho Lee, MD3, Dong Wook Shin, MD, DrPH4

1ON Clinic, Seoul, Korea
2Isu Lamar Clinic, Seoul, Korea
3BESTOP Clinic, Suwon, Korea
4Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Correspondence to: Dong Wook Shin
Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea

Received: October 13, 2020; Accepted: October 23, 2020

This is an open access article distributed under the terms of the Creative Commons Attribution Non- Commercial License ( which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background and Objectives
The use of botulinum toxin injections in cosmetic procedures is widely practiced in aesthetic medicine. Recently, various toxin products have been developed and are appearing in the medical market. We sought to document what clinicians consider important when selecting a toxin product, excluding price, which was found to be the most important factor in our previous study.
Materials and Methods
At the conference of the Korean Association for Laser, Dermatology, and Trichology (KALDAT) held on July 26, 2020, we conducted a web-based realtime survey to investigate the bases for clinicians’ decisions on botulinum toxin products, particularly what clinicians consider most important when selecting toxin products. In addition, we examined whether the purpose of the procedure affected their choices.
When clinicians chose a botulinum toxin product, the second most important factor after price was the stability of the toxin. This was the same for procedures to improve wrinkles and to reduce muscle volume.
The stability of toxin products is an essential aspect to achieving consistent and predictable results, and as such, clinicians consider it very important when selecting toxin products. Companies that are producing or preparing to develop botulinum toxin products should pay attention to securing and maintaining product stability.

Keywords: Botulinum toxin, Stability, Selection