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The AESTHETICS 2022; 3(2): 7-11

Published online October 30, 2022

© Korean Association For Laser Dermatology And Trichology

Clinical Guideline: Deoxycholic Acid Injection for Submental Fat Reduction

Hyoung-Moon Kim, MD, PhD1 , Yoo-Seock Ree, MD2, Min-Soo Park, MD2, Ji-Sun Kim, MD3, Ji-Hyun Ahn, MD4, Kyu-Ho Yi, MD5

1Maylin Clinic (Ilsan), Goyang, Korea
2Gangnam View Best Clinic, Pyeongtaek, Korea
3MH Clinic, Seoul, Korea
4Uahnclinic, Seoul, Korea
5Wonju Public Health Center, Wonju, Korea

Correspondence to: Hyoung-Moon Kim
Maylin Clinic (Ilsan), Goyang 10391, Korea

Received: November 14, 2022; Accepted: November 15, 2022

This is an open access article distributed under the terms of the Creative Commons Attribution Non- Commercial License ( which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background and Objectives
This purpose is to present guidelines for anatomical structure and correct injection method that must be known when injecting deoxycholic acid (DC), which is used for the purpose of reducing fat volume for submental fat hypertrophy.
Materials and Methods
The papers related to injectables used for fat volume reduction from 2000 to 2022 were searched on Google Scholar, related contents were summarized, and clinical photos of DC injection patients from November 2021 to June 2022 were compared and presented.
Anatomically, it is necessary to be careful when injecting the marginal mandibular nerve, mental artery, and submandibular gland. In particular, accurately measure the thickness of each patient’s submental fat. Care should be taken not to cause skin damage by injection. Therefore, it is most important to inject after confirming the anatomical boundary with ultrasound.
DC injection, which is performed after confirming major anatomical areas using ultrasound and accurate measurement of fat thickness, is effective way to reduce double chin fat volume.

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Keywords: V-olet, Deoxycholic acid, Submental fat, Submental artery, Submandibular gland, Hyoid bone, Anterior belly of digastric muscle